The Problem
Delayed diagnosis is a major cost to the economy
Bipolar disorder costs the US economy approximately $219 billion annually.
annual US spend on Bipolar disorder
Widespread misdiagnosis leads to a long diagnostic odyssey
70% of people are initially misdiagnosed with a third or more still undiagnosed over a decade later.
average time to diagnosis in the US
The human impact of the disease is severe
Frustrations and challenges are felt by both patients and families over many years.
people with Bipolar I are out of work
PUBLICATIONS
Translational PsychiatryA machine learning algorithm to differentiate bipolar disorder from major depressive disorder using an online mental health questionnaire and blood biomarker data
2021-12-01
Jakub Tomasik, Sung Yeon Sarah Han, Giles Barton-Owen, Dan-Mircea Mirea, Nayra A. Martin-Key, Nitin Rustogi, Santiago G. Lago, Tony Olmert, Jason D. Cooper, Sureyya Ozcan, Pawel Eljasz, Grégoire Thomas, Robin Tuytten, Tim Metcalfe, Thea S. Schei, Lynn P. Farrag, Lauren V. Friend, Emily Bell, Dan Cowell & Sabine Bahn
JMIR publicationsToward an Extended Definition of Major Depressive Disorder Symptomatology: Digital Assessment and Cross-validation Study
2021-02-15
Nayra A Martin-Key; Dan-Mircea Mirea; Tony Olmert; Jason Cooper; Sung Yeon Sarah Han; Giles Barton-Owen; Lynn Farrag5 ; Emily Bell5 ; Pawel Eljasz1 ; Daniel Cowell5, 6 ; Jakub Tomasik1 ; Sabine Bahn1, 5
JAMA PsychiatryMetabolomic Biomarker Signatures for Bipolar and Unipolar Depression
2023-10-25
Jakub Tomasik, Scott J. Harrison, Nitin Rustogi, Tony Olmert, Giles Barton-Owen, Sung Yeon Sarah Han, Jason D. Cooper, Paweł Eljasz, Lynn P. Farrag, Lauren V. Friend, Emily Bell, Dan Cowell, Sabine Bahn
Join us
Having published the cornerstone research in JAMA Psychiatry in October 2023, we have since validated the results in a further study with the paper due to be published Q1 2026. We're now actively engaging partners around further studies that will bring this research closer to clinical application.
